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货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN26384 | TCPOBOP | 76150-91-9 | TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss[1]. TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins[2]. |
CSN19741 | PK 11195 | 85532-75-8 | PK11195 is a 2‑Phenylindolylglyoxylyldipeptide Murine Double Minute2 (MDM2)/Translocator Protein (TSPO)/Human Constitutive Androstane Receptor (hCAR) Inhibitor, and is potentially useful for the Treatment of Gliomas. |
CSN26394 | CITCO | 338404-52-7 | CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. It inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors[1]. |
CSN23907 | CINPA1 | 102636-74-8 | CINPA1 is a CAR inhibitor capable of reducing CAR-mediated transcription with an IC50 of ∼70 nM. |
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